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Mangosteen Fruit Rind Extract
INCI: GARCINIA MANGOSTANA PEEL EXTRACT

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Product Identification

Product Name

Mangosteen Fruit Rind Extract

Product Code

GM003

CAS No.

90045-25-3

EC No.

289-884-9

INCI

GARCINIA MANGOSTANA PEEL EXTRACT

Description

Garcinia Mangostana Peel Extract is an extract of the peel of the Mangosteen, Garcinia mangostana L., Hypericaceae

 

Compositions/ Information on ingredients

Name

CAS No.

 

GARCINIA MANGOSTANA PEEL EXTRACT*

90106-37-9

 

Propylene glycol

57-55-6

 

Phenoxyethanol 1%

122-99-6

 

Caprylhydroxamic acid 0.05%

7377-03-9

 

*) See section method of preparation

**) Active content: alpha-mangostin not less than 1,500 mg%

Source of Botanical Raw Material

Botanical name

Garcinia mangostana L.

Part of plant used

Peel (fruit rind)

 

Physical Characterization

Physical state and appearance

Liquid

Color

Brown to Dark brown

Odor

Slightly characteristic

pH

4.0 +/- 1.0

Specific gravity

1.05 +/- 0.20

 

History of Traditional Use/ Claim Support

Used

References

Skin conditioning

Cosmetic Ingredient Database. http://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=56319
Accessed: 26 Sep 2017

Antioxidant

Pothitirat, W., Chomnawang, M.T., Supabphol, R., Gritsanapan, W. (2009) Comparison of bioactive compounds content, free radical scavenging and anti-acne inducing bacteria activities of extracts from the mangosteen fruit rind at two stages of maturity. Fitoterapia 80: 442-447.

Suttirak, W., Manurakchinakorn, S. (2014) In vitro antioxidant properties of mangosteen peel extract. Journal of Food Science and Technology 51: 3546-3548.

Anti-inflammatory

Itoh, T., Ohiguchi, K., Iinuma, M., Nozawa, Y., Akao, Y. (2008) Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation. Bioorganic & Medicinal Chemistry 16: 4500-4508.

Anti-allergenic

Nakatani, K., Atsumi, M., Arakawa, T., Oosawa, K., Shimura, S., Nakahata, N., Ohizumi, Y. (2002) Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biological and Pharmaceutical Bulletin 25: 1137-1141.

Protect against skin cancer

Wang, J.J., Sanderson, B.J., Zhang, W. (2011) Cytotoxic effect of xanthones from pericarp of the tropical fruit mangosteen (Garcinia mangostana Linn.) on human melanoma cells. Food and Chemical Toxicology 49: 2385-2391.

Anti-acne

Pothitirat, W., Chomnawang, M.T., Supabphol, R., Gritsanapan, W. (2009) Comparison of bioactive compounds content, free radical scavenging and anti-acne inducing bacteria activities of extracts from the mangosteen fruit rind at two stages of maturity. Fitoterapia 80: 442-447.

 

Method of Preparation

Process of extraction

Maceration and/or sonication

Extracting solvent

Ethanol

Concentration

Distillation in vacuo

Fractionation

-

Plant Extract Ratio

Between 1:1.5 to 1:1

Solubility of the preparation

Alcohol, Water

 

Microbial test

Microbial test

เป็นไปตามข้อกำหนดด้านจุลชีววิทยาตามประกาศกระทรวงสาธารณสุข เรื่อง กำหนดลักษณะของเครื่องสำอางที่ห้ามผลิต นำเข้า หรือขาย พ.ศ. 2559 และ

Conformed with microbial limits described in the Thai regulation prescribing the category of cosmetics which may not be manufactured B.E.2559 and:

Total plate count

< 1000 CFU/g

Total yeast and mold

< 1000 CFU/g

 
   

 

Chemical Characterization

Analysis method

HPLC and/or TLC

Active content

Alpha-mangostin not less than 1,500 mg%

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