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Mulberry Leaf extract
INCI: MORUS ALBA LEAF EXTRACT

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Product Identification

Product Name

Mulberry leaf extract

Product Code

ML003

CAS No.

94167-05-2

EC No.

303-403-2

INCI

MORUS ALBA LEAF EXTRACT

Description

Morus Alba Leaf Extract is an extract of the dried leaves of the Mulberry, Morus alba L., Moraceae

 

Compositions/ Information on ingredients

Name

CAS No.

 

MORUS ALBA LEAF EXTRACT *

94167-05-2

 

Propylene glycol

57-55-6

 

Phenoxyethanol 1%

122-99-6

 

Caprylhydroxamic acid 0.05%

7377-03-9

 

*) See section method of preparation

 

Cosmetic Restriction: N/A

 

Source of Botanical Raw Material

Botanical name

Morus alba L.

Part of plant used

LEAF

 

Physical Characterization

Physical state and appearance

Liquid

Color

Green to Dark Green

Odor

Slightly characteristic

pH

6.0 +/- 1.0

Specific gravity

1.00 +/- 0.20

 

History of Traditional Use/ Claim Support

Used

References

Skin conditioning

Cosmetic Ingredient Database. http://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=56975
Accessed: 14 May 2018

Antioxidant

Liao, B.Y., Zhu, D.Y., Thakur, K., Li, L., Zhang, J.G., Wei, Z.J. (2017) Thermal and Antioxidant Properties of Polysaccharides Sequentially Extracted from Mulberry Leaves (Morus alba L.). Molecules. 22(12): e2271.

Protected of skin damage

Woo, H., Lee, J., Park, D., Jung, E. (2017) Protective Effect of Mulberry (Morus alba L.) Extract against Benzo[a]pyrene Induced Skin Damage through Inhibition of Aryl Hydrocarbon Receptor Signaling. Journal of Agricultural and Food Chemsitry. 65(50):10925-10932.

Lipolytic

Lee, M.R., Kim, J.E., Yun, W.B., Choi, J.Y., Park, J.J., Kim, H.R., Song, B.R., Choi, Y.W., Kim, K.M., Hwang, D.Y. (2017) Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats. Laboratory Animal Research. 33(3):270-279.

Li, H.X., Jo, E., Myung, C.S., Kim, Y.H., Yang, S.Y. (2017) Lipolytic effect of compounds isolated from leaves of mulberry (Morus alba L.) in 3T3-L1 adipocytes. Natural Product Research. 19:1-4.

Antimicrobial

Gunjal, S., Ankola, A.V., Bhat, K. (2015) In vitro antibacterial activity of ethanolic extract of Morus alba leaf against periodontal pathogens. Indian Journal of Dental Research. 26(5): 533-536.

Anti-inflammatory

Chen, Y.C., Tien, Y.J., Chen, C.H., Beltran, F.N., Amor, E.C., Wang, R.J., Wu, D.J., Mettling, C., Lin, Y.L. Yang, W.C. (2013) Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration involving MEK-ERK signaling. BMC Complementary and Alternative Medicine. 13:45.

 

Method of Preparation

Process of extraction

Maceration and/or sonication

Extracting solvent

Ethanol

Concentration

Distillation in vacuo

Fractionation

None

Plant Extract Ratio

Between 1:1.5 to 1:1

Solubility of the preparation

Alcohol, Water

 

Microbial test

เป็นไปตามข้อกำหนดด้านจุลชีววิทยาตามประกาศกระทรวงสาธารณสุข เรื่อง กำหนดลักษณะของเครื่องสำอางที่ห้ามผลิต นำเข้า หรือขาย พ.ศ. 2559 และ

Conformed with microbial limits described in the Thai regulation prescribing the category of cosmetics which may not be manufactured B.E.2559 and:

Total plate count

< 1000 CFU/g

Total yeast and mold

< 1000 CFU/g

 

Chemical Characterization

Analysis method

HPLC and/or TLC

Active content

Rutin

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