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Pueraria mirifica extract
INCI: PUERARIA MIRIFICA ROOT EXTRACT

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Product Identification

Product Name

Pueraria mirifica extract

Product Code

PM003

CAS No.

-

EC No.

-

INCI

PUERARIA MIRIFICA ROOT EXTRACT

Description

Pueraria Mirifica Root Extract is an extract of the roots of Pueraria mirifica, Fabaceae

 

Compositions/ Information on ingredients

Name

CAS No.

   

PUERARIA MIRIFICA ROOT EXTRACT *

-

   

Propylene glycol

57-55-6

   

Phenoxyethanol 1%

122-99-6

   

Caprylhydroxamic acid 0.05%

7377-03-9

   

*) See section method of preparation

 

Cosmetic Restriction:

Thai regulation: Total Pueraria mirifica extract and Butea superba extract calculated as crude plant dried powder should not exceed 100 mg/day.

 

Source of Botanical Raw Material

Botanical name

Pueraria mirifica

Part of plant used

Root

 

Physical Characterization

Physical state and appearance

Liquid

Color

Yellow to brownish

Odor

Slightly characteristic

pH

5.0 +/- 1.0

Specific gravity

1.02 +/- 0.20

 

History of Traditional Use/ Claim Support

Used

References

Skin conditioning

Cosmetic Ingredient Database. http://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=58700
Accessed: 20 May 2018

Estrogenic effect

Kakehashi, A., Yoshida, M., Tago, Y., Ishii, N., Okuno, T., Gi, M., Wanibuchi, H. (2016) Pueraria mirifica Exerts Estrogenic Effects in the Mammary Gland and Uterus and Promotes Mammary Carcinogenesis in Donryu Rats. Toxins. 8(11): 275.

Loutchanwoot, P., Vortherms, T., Jarry, H. (2016) Evaluation of in vivo estrogenic potency of natural estrogen-active chemical, puerarin, on pituitary function in gonadectomized female rats. Life Sciences. 165: 75-82.

Suwanvesh, N., Manonai, J., Sophonsritsuk, A., Cherdshewasart, W. (2017) Comparison of Pueraria mirifica gel and conjugated equine estrogen cream effects on vaginal health in postmenopausal women. Menopause. 24(2): 210-215.

Antioxidant

Chatuphonprasert, W., Udomsuk, L., Monthakantirat, O., Churikhit, Y., Putalun, W., Jarukamjorn, K. (2013) Effects of Pueraria mirifica and miroestrol on the antioxidation-related enzymes in ovariectomized mice. The Journal of Pharmacy and Pharmacology. 65(3): 447-456.

Cherdshewasart, W., Sutjit, W. (2008) Correlation of antioxidant activity and major isoflavonoid contents of the phytoestrogen-rich Pueraria mirifica and Pueraria lobata tubers. Phytomedicine 15(1-2): 38-43.

 

Method of Preparation

Process of extraction

Maceration and/or sonication

Extracting solvent

Ethanol

Concentration

Distillation in vacuo

Fractionation

None

Plant Extract Ratio

Between 1:1.5 to 1:1

Solubility of the preparation

Alcohol, Water

 

Microbial test

เป็นไปตามข้อกำหนดด้านจุลชีววิทยาตามประกาศกระทรวงสาธารณสุข เรื่อง กำหนดลักษณะของเครื่องสำอางที่ห้ามผลิต นำเข้า หรือขาย พ.ศ. 2559 และ

Conformed with microbial limits described in the Thai regulation prescribing the category of cosmetics which may not be manufactured B.E.2559 and:

Total plate count

< 1000 CFU/g

Total yeast and mold

< 1000 CFU/g

 

Chemical Characterization

Analysis method

HPLC and/or TLC

Active content

Puerarin

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